747 adv is on the back burner until 787 development is complete - the boys (and girls) in Everett are up to their collective fannies in 787 development right now - not enough manpower to try to do a 747 major overhaul at the same time. Renton engineering (narrow body) is doing the MMA (Navy replacement for P-3 based on 737) so they have lots of work as well.
Talk was to use the 787 engine technology to increase fuel economy for the 747adv.
That means a LOT of other "little" changes. <sarcasm mode off>